Analysis of clinical characteristics and risk factors between elderly patients with severe and nonsevere Omicron variant infection

Table 2 Univariate and multivariate analysis of the development of severe infection in elderly patients with coronavirus disease 2019

Variables	Univariate analysis OR (95%CI)	P value	Multivariate analysis OR (95%CI)	P value
Age	1.084 (0.978, 1.202)	0.126	-	-
Sex	0.575 (0.1, 3.322)	0.536	-	-
Vaccinations	0.636 (0.039, 10.385)	0.751	-	-
Chronic respiratory disease	0.559 (0.025, 12.453)	0.713	-	-
Diabetes mellitus	7.76 (0.446, 134.92)	0.16	-	-
Hypertension	3.267 (0.365, 29.275)	0.29	-	-
Coronary heart disease	0.142 (0.01, 1.926)	0.142	-	-
Cerebral infarction	7.757 (0.704, 85.443)	0.094	4.26 (1.012, 17.937)	0.048
Chronic kidney disease	0.057 (0.001, 4.578)	0.2	-	-
Neurodegenerative diseases	19.385 (0.149, 2527.003)	0.233	-	-
Neoplastic disease	0.527 (0.022, 12.846)	0.695	-	-
Immune system disease	0 (0, 203.169)	0.213	-	-
WBC	1.096 (0.669, 1.794)	0.716	-	-
Neutrophil percentage	1.125 (0.95, 1.331)	0.172	-	-
eGFR	1.044 (0.966, 1.128)	0.281	-	-
NLR	1.017 (0.636, 1.626)	0.943	-	-
SIRI	1.003 (0.534, 1.883)	0.993	-	-
CRP	1.023 (0.984, 1.063)	0.251	-	-
PCT	1.552 (0.67, 3.598)	0.305	-	-
Oxygen saturation	0.513 (0.369, 0.714)	0.000	0.573 (0.451, 0.728)	0.000
Lactic acid	0.768 (0.269, 2.194)	0.622	-	-
D-dimers	1.156 (0.754, 1.772)	0.507	1.394 (1, 1.944)	0.05
Viral shedding time	1.066 (0.892, 1.274)	0.484	-	-
Lianhua Qingwen Granule	0.486 (0.055, 4.302)	0.517	-	-
Paxlovid	2.505 (0.19, 33.049)	0.485	-	-

Bold letters represent significant predictors of the development of severe infection in elderly patients with coronavirus disease 2019. OR: Odds ratio; CI: Confidence interval; eGFR: Estimated glomerular filtration rate; NLR: Neutrophil to lymphocyte ratio; SIRI: Systemic inflammatory response index; CRP: C-reactive protein; PCT: Procalcitonin; WBC: White blood cell.