Three-dimensional models of antigens with serodiagnostic potential for leprosy: An in silico study

doi:10.5495/wjcid.v13.i1.1

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Feb 28, 2023 (publication date) through Aug 25, 2024

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World Journal of Clinical Infectious Diseases

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2220-3176

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Infect Dis. Feb 28, 2023; 13(1): 1-10
Published online Feb 28, 2023. doi: 10.5495/wjcid.v13.i1.1

Table 2 Validation of three-dimensional models of the Mycobacterium leprae antigens

Antigen	Identification	Functional structure	MolProbity Score	Ramachandran plot^a (%)	Outliers (%)
ML2038	Bacterioferritin	Homopolymer	1.31	98.48	0.08
ML0050	ESAT-6-like protein esxB	Monomer	0.77	98.61	0.00
ML0286	Fructose-bisphosphate aldolase	Homotetramer	1.32	96.47	0.59
85B Ag	85B antigen	Monomer	1.85	93.95	0.00

^aResidues in favorable regions.

Citation: Melo de Assis BL, Viana Vieira R, Rudenco Gomes Palma IT, Bertolini Coutinho M, de Moura J, Peiter GC, Teixeira KN. Three-dimensional models of antigens with serodiagnostic potential for leprosy: An in silico study. World J Clin Infect Dis 2023; 13(1): 1-10
URL: https://www.wjgnet.com/2220-3176/full/v13/i1/1.htm
DOI: https://dx.doi.org/10.5495/wjcid.v13.i1.1