Mutations of the brpR and brpS genes affect biofilm formation in Staphylococcus aureus

Figure 6 Comparison of the sequences and predicted topologies of the putative two-component system membrane sensor BrpS (left, Staphylococcus aureus) and BrsM (right, Streptococcus mutans). According to this prediction, residues likely to be reactive (red) are topologically arranged in similar loci among both proteins. Intra is proposed to correspond with the cytoplasmic space, and extra is proposed to correspond with the extracellular milieu of the cell. Figures generated by Protter.