Mutations of the brpR and brpS genes affect biofilm formation in Staphylococcus aureus

Figure 4 Bioinformatic comparison of the BrsRM proteins of Streptococcus mutans with the BrpRS proteins of Staphylococcus aureus. A: BrsM, a two-component system membrane protein responsible for activating competence in response to sensing competitor organisms within a niche, shares sequence similarity with BrpS; B: BrsR, which is the cognate response regulator to BrsM, shares sequence similarity with BrpR. BLASTp NCBI. Algorithm parameters: Max target sequences = 100, automatically adjusted parameters for short input sequences, expect threshold = 10, word size = 3, max matches in a query range = 0, matrix = BLOSUM62, gap costs = 11 existence and 1 extension, and a conditional compositional score matrix adjustment.