Mutations of the brpR and brpS genes affect biofilm formation in Staphylococcus aureus

Figure 2 Effect of brpR and brpS mutations and complementation on Staphylococcus aureus biofilm formation. All experiments represent the mean ± SD from five different runs done in triplicate for each strain. Biofilm formation was done on wild-type Staphylococcus aureus (S. aureus) strain Newman (WT, open column), S. aureus Newman srtA mutant (black column), S. aureus Newman brpS mutant (right striped column), S. aureus Newman brpS mutant/pAMZ1-3 (left striped column), S. aureus Newman brpR mutant (dark right striped column), and S. aureus Newman brpR mutant/pXB31 (dark left striped column). Differences were statistically compared by analysis of variance where ^aP < 0.001.