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World J Clin Infect Dis. Dec 30, 2011; 1(1): 4-10
Published online Dec 30, 2011. doi: 10.5495/wjcid.v1.i1.4
Published online Dec 30, 2011. doi: 10.5495/wjcid.v1.i1.4
Species | Antifungal agent | Statin | Interaction | Ref. |
Yeasts | ||||
Candida albicans | AMB | ATO, FLV | ADD | [28,21] |
FCZ, ITZ, KTZ | ATO | ADD | [29] | |
FCZ, ITZ | FLV | ADD, SYN, NI | [21,23,29] | |
LOV | SYN, ADD | [22,29] | ||
FCZ, ITZ, KTZ, MCZ | PRA | NI | [23,29] | |
FCZ, KTZ | ROS | ADD | [29] | |
FCZ, ITZ, KTZ | SIM | ADD | [29] | |
ITZ, KTZ, MCZ | FLV, LOV | ADD | [29] | |
ITZ, MCZ | ROS | SYN, ADD | [29] | |
MCZ | ATO, SIM | SYN, ADD | [29] | |
PN, NYS | FLV, LOV, SIM | ADD | [18,28] | |
Candida glabrata | AMB | ATO, ROS | ADD | [18] |
FCZ | ATO | SYN, ADD | [29] | |
FCZ, ITZ | FLV | ADD, NI | [21,29] | |
FCZ | LOV | SYN, ADD | [29] | |
FCZ, ITZ | PRA | NI | [29] | |
FCZ, ITZ, KTZ, MCZ | ROS, SIM | ADD | [29] | |
ITZ, KTZ, MCZ | ATO, FLV, ROS | ADD | [29] | |
KTZ, MCZ | PRA | ADD | [29] | |
PN | ATO, FLV | ADD | [18] | |
LOV, SIM | ADD, SYN | [18] | ||
NYS | LOV, ROS | ADD | [28] | |
Candida parapsilosis | FCZ, ITZ | FLV | ADD, SYN | [21] |
Candida tropicalis | FCZ | FLV | SYN | [21] |
ITZ | FLV | ADD, SYN | [21] | |
Cryptococcus neoformans | FCZ, ITZ | FLV | ADD, SYN | [21] |
AMB | FLV | ADD | [21] | |
Filamentous fungi-Zygomycetes | ||||
Absidia corymbifera | AMB | ROS | ADD, SYN | [19] |
Cunninghamella bertholletiae | VCZ | LOV | SYN | [33] |
Mucor circinelloides | VCZ | LOV | SYN | [33] |
Rhizomucor mieheii | AMB | FLV, ROS | ADD, SYN | [19] |
Rhizopus homothallicus | VCZ | LOV | SYN | [33] |
Rhizopus microsporus var. oligosporus | AMB | FLV, ROS | ADD, SYN | [19] |
Rhizopus oryzae | AMB | FLV, ROS | ADD, SYN | [19,28] |
ATO, SIM | ADD | [28] | ||
FCZ | FLV | NI | [29] | |
FCZ, ITZ, MCZ | LOV | ADD | [29] | |
ITZ, KTZ | ATO, FLV, ROS | SYN, ADD | [29] | |
ITZ, KTZ, MCZ | PRA | NI | [29] | |
ITZ, KTZ | SIM | NI | [29] | |
KTZ | LOV | NI | [29] | |
MCZ | ATO | NI | [29] | |
FLV, ROS, SIM | ADD | [29] | ||
NYS | ATO, FLV, LOV | ADD | [28] | |
PN | ATO | ADD | [18] | |
LOV, ROS | SYN | [18] | ||
VCZ | LOV | SYN | [33] | |
Syncephalastrum racemosum | AMB | FLV, ROS | ADD, SYN | [28] |
Filamentous fungi-Ascomycetes | ||||
Aspergillus flavus | AMB, PN | FLV | ADD, SYN | [18,28] |
ITZ | ATO | SYN | [29] | |
ITZ, KTZ, MCZ | FLV | SYN, ADD | [29] | |
ITZ | LOV | ADD | [29] | |
ITZ, KTZ | PRA | NI | [29] | |
ITZ | ROS | ADD | [29] | |
ITZ, MCZ | SIM | ADD | [29] | |
KTZ | ATO, ROS | SYN, ADD | [29] | |
SIM | NI | [29] | ||
MCZ | ATO, LOV, ROS | NI | [29] | |
PRA | ADD | [29] | ||
Aspergillus fumigatus | AMB | ATO, FLV | ADD, SYN | [28,37] |
CFG, VCZ | FLV | SYN | [37] | |
FCZ, ITZ | ATO | SYN | [29] | |
FCZ, ITZ, MCZ | FLV | ADD | [29] | |
FCZ | LOV | SYN | [29] | |
FCZ | SIM | SYN, ADD | [29] | |
ITZ, KTZ, MCZ | LOV, SIM | ADD | [29] | |
PRA | NI | [29] | ||
ITZ | ROS | SYN, ADD | [29] | |
KTZ, MCZ | ATO | SYN, ADD | [29] | |
KTZ | FLV | SYN, ADD | [29] | |
KTZ, MCZ | ROS | ADD | [29] | |
Paecilomyces variotii | AMB | ATO,SIM | ADD | [28] |
PN | FLV, LOV, SIM | SYN | [18] | |
Filamentous fungi-Heterokontophyta | ||||
Pythium insidiosum | TBF | FLV | ANT | [37] |
- Citation: Galgóczy L, Nyilasi I, Papp T, Vágvölgyi C. Statins as antifungal agents. World J Clin Infect Dis 2011; 1(1): 4-10
- URL: https://www.wjgnet.com/2220-3176/full/v1/i1/4.htm
- DOI: https://dx.doi.org/10.5495/wjcid.v1.i1.4