Editorial
Copyright ©2011 Baishideng Publishing Group Co.
World J Clin Infect Dis. Dec 30, 2011; 1(1): 4-10
Published online Dec 30, 2011. doi: 10.5495/wjcid.v1.i1.4
Table 3 Revealed in vitro interactions between statins and clinically used antifungal agents against different fungi
SpeciesAntifungal agentStatinInteractionRef.
Yeasts
Candida albicansAMBATO, FLVADD[28,21]
FCZ, ITZ, KTZATOADD[29]
FCZ, ITZFLVADD, SYN, NI[21,23,29]
LOVSYN, ADD[22,29]
FCZ, ITZ, KTZ, MCZPRANI[23,29]
FCZ, KTZROSADD[29]
FCZ, ITZ, KTZSIMADD[29]
ITZ, KTZ, MCZFLV, LOVADD[29]
ITZ, MCZROSSYN, ADD[29]
MCZATO, SIMSYN, ADD[29]
PN, NYSFLV, LOV, SIMADD[18,28]
Candida glabrataAMBATO, ROSADD[18]
FCZATOSYN, ADD[29]
FCZ, ITZFLVADD, NI[21,29]
FCZLOVSYN, ADD[29]
FCZ, ITZPRANI[29]
FCZ, ITZ, KTZ, MCZROS, SIMADD[29]
ITZ, KTZ, MCZATO, FLV, ROSADD[29]
KTZ, MCZPRAADD[29]
PNATO, FLVADD[18]
LOV, SIMADD, SYN[18]
NYSLOV, ROSADD[28]
Candida parapsilosisFCZ, ITZFLVADD, SYN[21]
Candida tropicalisFCZFLVSYN[21]
ITZFLVADD, SYN[21]
Cryptococcus neoformansFCZ, ITZFLVADD, SYN[21]
AMBFLVADD[21]
Filamentous fungi-Zygomycetes
Absidia corymbiferaAMBROSADD, SYN[19]
Cunninghamella bertholletiaeVCZLOVSYN[33]
Mucor circinelloidesVCZLOVSYN[33]
Rhizomucor mieheiiAMBFLV, ROSADD, SYN[19]
Rhizopus homothallicusVCZLOVSYN[33]
Rhizopus microsporus var. oligosporusAMBFLV, ROSADD, SYN[19]
Rhizopus oryzaeAMBFLV, ROSADD, SYN[19,28]
ATO, SIMADD[28]
FCZFLVNI[29]
FCZ, ITZ, MCZLOVADD[29]
ITZ, KTZATO, FLV, ROSSYN, ADD[29]
ITZ, KTZ, MCZPRANI[29]
ITZ, KTZSIMNI[29]
KTZLOVNI[29]
MCZATONI[29]
FLV, ROS, SIMADD[29]
NYSATO, FLV, LOVADD[28]
PNATOADD[18]
LOV, ROSSYN[18]
VCZLOVSYN[33]
Syncephalastrum racemosumAMBFLV, ROSADD, SYN[28]
Filamentous fungi-Ascomycetes
Aspergillus flavusAMB, PNFLVADD, SYN[18,28]
ITZATOSYN[29]
ITZ, KTZ, MCZFLVSYN, ADD[29]
ITZLOVADD[29]
ITZ, KTZPRANI[29]
ITZROSADD[29]
ITZ, MCZSIMADD[29]
KTZATO, ROSSYN, ADD[29]
SIMNI[29]
MCZATO, LOV, ROSNI[29]
PRAADD[29]
Aspergillus fumigatusAMBATO, FLVADD, SYN[28,37]
CFG, VCZFLVSYN[37]
FCZ, ITZATOSYN[29]
FCZ, ITZ, MCZFLVADD[29]
FCZLOVSYN[29]
FCZSIMSYN, ADD[29]
ITZ, KTZ, MCZLOV, SIMADD[29]
PRANI[29]
ITZROSSYN, ADD[29]
KTZ, MCZATOSYN, ADD[29]
KTZFLVSYN, ADD[29]
KTZ, MCZROSADD[29]
Paecilomyces variotiiAMBATO,SIMADD[28]
PNFLV, LOV, SIMSYN[18]
Filamentous fungi-Heterokontophyta
Pythium insidiosumTBFFLVANT[37]