Loss of cavin1 and expression of p-caveolin-1 in pulmonary hypertension: Possible role in neointima formation

Figure 4 A representative western blot and bar graph depicting the expression of cav-1 and Tyr 14 p-cav-1 in the lungs from controls (C), Monocrotaline (MCT, M), hypoxia (H) and MCT + Hypoxia (M+H) groups (n = 5-6). β-actin was used as a loading control. There is a significant loss of cav-1 in M group, but in M + H group, cav-1 expression is nearly normal. P-cav-1 is increased in M and M+H groups. Cav-1 expression in the H group is not altered, and p-cav-1 expression is not observed. ^aP < 0.05 vs C.