Association between G-protein β3 subunit gene and isolated systolic blood pressure elevation of greater than 130 mmHg: A large-scale cross-sectional study in the Japanese population

Table 1 Characteristics of the subjects

	Male			Female
	Cases mean ± SD	Controls mean ± SD	P-value1	Cases mean ± SD	Controls mean ± SD	P-value1
Age ≤ 49 yr	n = 390	n = 1423		n = 256	n = 2917
Age, yr	37.9 ± 7.8	37.6 ± 7.7	0.53	41.4 ± 7.1	36.7 ± 8.0	< 0.001
BMI, kg/m2	24.4 ± 3.3	23.2 ± 3.1	< 0.001	23.7 ± 4.4	21.5 ± 3.1	< 0.001
SBP, mmHg	135.2 ± 6.9	114.7 ± 8.9	< 0.001	135.3 ± 6.4	109.4 ± 10.1	< 0.001
DBP, mmHg	77.6 ± 5.2	71.1 ± 7.7	< 0.001	76.2 ± 6.5	66.7 ± 8.2	< 0.001
Age ≥ 50 yr	n = 925	n = 1675		n = 1226	n = 2196
Age, yr	66.9 ± 9.8	63.3 ± 9.7	< 0.001	67.0 ± 9.7	61.8 ± 9.1	< 0.001
BMI, kg/m2	23.3 ± 3.0	22.7 ± 3.0	< 0.001	23.0 ± 3.4	22.3 ± 2.9	< 0.001
SBP, mmHg	138.7 ± 8.8	115.3 ± 9.5	< 0.001	139.4 ± 9.6	114.1 ± 10.0	< 0.001
DBP, mmHg	76.6 ± 6.1	70.5 ± 7.8	< 0.001	75.2 ± 6.7	68.8 ± 8.0	< 0.001

¹t-test. DBP: Diastolic blood pressure; BMI: Body mass index; SBP: Systolic blood pressure.