RhoA signaling and blood pressure: The consequence of failing to &ldquo;Tone it Down&rdquo;

doi:10.5494/wjh.v6.i1.18

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Feb 23, 2016 (publication date) through Feb 8, 2025

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World Journal of Hypertension

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2220-3168

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hypertens. Feb 23, 2016; 6(1): 18-35
Published online Feb 23, 2016. doi: 10.5494/wjh.v6.i1.18

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Figure 3 Pharmacologic and genetic regulation of the RhoA signaling axis. Schematic indicating the sites of action of pharmacological inhibitors (bold) of RhoA signaling molecules. Polymorphisms (SNPs/eQTLs) that could influence RhoA signaling are also shown. AJ: Adherens junction; A2R: Angiotensin type II receptor; ARBs: Angiotensin receptor blockers; ACEIs: Angiotensin converting enzyme inhibitors; ASAH1: Acid ceramidase; SPHK1: Sphingosine kinase 1.

Citation: Bai X, Dee R, Mangum KD, Mack CP, Taylor JM. RhoA signaling and blood pressure: The consequence of failing to “Tone it Down”. World J Hypertens 2016; 6(1): 18-35
URL: https://www.wjgnet.com/2220-3168/full/v6/i1/18.htm
DOI: https://dx.doi.org/10.5494/wjh.v6.i1.18