Therapeutics Advances
Copyright ©The Author(s) 2016.
World J Hypertens. Feb 23, 2016; 6(1): 1-17
Published online Feb 23, 2016. doi: 10.5494/wjh.v6.i1.1
Table 2 Cellular functions controlled by the RhoA/Rho kinase pathway[7-9]
Cytoskeletal dynamics and actin organization (formation of stress fibers and focal adhesion complexes)
Cell contraction
Adhesion
Morphology
Motility
Transcriptional regulation (pro remodeling genes)
Cell proliferation and cytokinesis
Differentiation
Apoptosis
Insulin-stimulated insulin receptor substrate-1 phosphorylation
Development