Progress in neuregulin/ErbB signaling and chronic heart failure

doi:10.5494/wjh.v5.i2.63

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May 23, 2015 (publication date) through Jan 3, 2025

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World Journal of Hypertension

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2220-3168

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Hypertens. May 23, 2015; 5(2): 63-73
Published online May 23, 2015. doi: 10.5494/wjh.v5.i2.63

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Figure 1 Role of neuregulin-1/ErbB signaling in heart. Neuregulin (NRG)-1 treatment affects various signaling pathways as well as leads to changes in cell metabolism and epigenetic modification that more closely resemble normal heart function. Akt: Protein kinase B; cMLK: Cardiac myosin light-chain kinase; eNOS: Endothelial nitric oxide synthase; Erk: Extracellular signal-regulated kinase; FAK: Focal adhesion kinase; MLC: Myosin light chain; PLB: Phospholamban; PP1: Protein phosphatase 1; SERCA2a: Sarcoplasmic reticulum Ca²⁺-ATPase 2a.

Citation: Yin HK, Li XY, Jiang ZG, Zhou MD. Progress in neuregulin/ErbB signaling and chronic heart failure. World J Hypertens 2015; 5(2): 63-73
URL: https://www.wjgnet.com/2220-3168/full/v5/i2/63.htm
DOI: https://dx.doi.org/10.5494/wjh.v5.i2.63