Editorial
Copyright ©2012 Baishideng.
World J Hypertens. Jun 23, 2012; 2(3): 29-33
Published online Jun 23, 2012. doi: 10.5494/wjh.v2.i3.29
Figure 1
Figure 1 Roles of cathepsins and cystatin C in the pathogenesis of heart and kidney diseases. A schematic model of cathepsin regulation and function in cardiorenal cells is shown. Tissue and circulating cathepsins (Cats) were used as biomarkers for the diagnosis of cardiorenal disease. Ang I: Angiotensin II; AT1R: Ang II type 1 receptor; IL-1β: Interleukin-1β; TNF-α:Tumor necrosis factor-α; TNFR: TNF-α receptor; ILR: IL-1β receptor; ECM: Extracellular matrix; NADPH: Nicotinamide adenine dinucleotide phosphate.