Diarylpentanoid, a curcumin analog, inhibits malignant meningioma growth in both in vitro and in vivo models

doi:10.5493/wjem.v15.i2.102897

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World Journal of Experimental Medicine

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2220-315x

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Exp Med. Jun 20, 2025; 15(2): 102897
Published online Jun 20, 2025. doi: 10.5493/wjem.v15.i2.102897

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Figure 6 Apoptosis induction in meningioma cell lines with GO-Y030 in vitro. A: Cleaved Caspase 3 in the control of IOMM-Lee; B: Cleaved Caspase 3 induction of IOMM-Lee treated with GO-Y030 at twice concentration of the 50% inhibitory concentration (IC₅₀ × 2); C: The percentage of Cleaved Caspase 3 positive cells in IOMM-Lee treated with GO-Y030 at IC₅₀ × 2; D: Cleaved Caspase 3 in the control of HKBMM; E: Cleaved Caspase 3 induction of HKBMM treated with GO-Y030 at IC₅₀ × 2; F: The percentage of Cleaved Caspase 3 positive cells in HKBMM treated with GO-Y030 at IC₅₀ × 2.

Citation: Terasawa A, Shimazu K, Nanjo H, Miura M, Shibata H. Diarylpentanoid, a curcumin analog, inhibits malignant meningioma growth in both in vitro and in vivo models. World J Exp Med 2025; 15(2): 102897
URL: https://www.wjgnet.com/2220-315x/full/v15/i2/102897.htm
DOI: https://dx.doi.org/10.5493/wjem.v15.i2.102897