Hypoxia-inducible factor-1α at the invasive tumor front in oral squamous cell carcinoma

Figure 3  Correlation of hypoxia-inducible factor 1-alpha expression with E-cadherin expression. A: Immunohistochemical expression of hypoxia-inducible factor 1-alpha (HIF-1α); B: E-cadherin expression. No significant correlation was found between HIF-1α and E-cadherin expression (P = 0.287). (Immunohistochemistry, 9 × magnification); C: HIF-1α expression (green); D: E-cadherin expression (magenta); E: Colocalization of HIF-1α and E-cadherin (white) in images obtained via confocal microscopy (Immunofluorescence, 20 × magnification); F: No significant correlation was found between HIF-1α and E-cadherin expression (P = 0.287).