Matrix metalloproteinases and their tissue inhibitors as indicators of aortic aneurysm and dissection development in extracellular matrix remodeling

Figure 1 An example of the distribution differences of matrix metalloproteinas-1 and matrix metalloproteinas-9 between aneurysm and dissection. The charts illustrate the absolute mean values (%) of immunohistological detection of the corresponding target antigens in the adventitia and media for the groups “aneurysm” and “dissection” (n = 52 each). Minimal staining was observed in the intima. Grading evaluations were conducted independently by two observers/pathologists. MMPs: Matrix metalloproteinases.