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©The Author(s) 2024.
World J Exp Med. Sep 20, 2024; 14(3): 93869
Published online Sep 20, 2024. doi: 10.5493/wjem.v14.i3.93869
Published online Sep 20, 2024. doi: 10.5493/wjem.v14.i3.93869
Table 3 Multivariate cox proportional hazard regression analyses of factors affecting all-cause mortality and cancer related mortality among United States patients diagnosed with anaplastic thyroid cancer between 2010 and 2017
Characteristics | Overall mortality | Cancer related mortality |
Adjusted proportional, HR (95%CI) | Adjusted proportional, HR (95%CI) | |
Gender | ||
Female | 1 (Reference) | 1 (Reference) |
Male | 1.11 (0.89-1.38) | 1.09 (0.87-1.36) |
Age at diagnosis, year old | ||
00-59 | 1 (Reference) | 1 (Reference) |
60-79 | 2.85 (0.61-13.43) | 2.16 (0.46-10.18) |
80 + | 2.01 (0.40-10.18) | 1.48 (0.29-7.60) |
Marital status | ||
Married | 1 (Reference) | 1 (Reference) |
Single | 1.00 (0.75-1.34) | 0.94 (0.69-1.26) |
Divorced/separated | 0.63 (0.42-0.94)a | 0.61 (0.40-0.92)a |
Widowed | 1.03 (0.78-1.37) | 1.03 (0.77-1.37) |
Tumor stage | ||
Localized | 1 (Reference) | 1 (Reference) |
Regional by direct extension only | 6.26 (1.29-30.42)a | 5.05 (1.05-24.19)a |
Regional lymph nodes involved only | 2.71 (0.42-17.49) | 2.30 (0.36-14.68) |
Regional by both direct extension and lymph node involvement | 3.58 (0.74-17.31) | 2.97 (0.62-14.15) |
Distant | 5.73 (1.34-24.51)a | 4.57 (1.08-19.29)a |
Race | ||
Non-Hispanic white | 1 (Reference) | 1 (Reference) |
Non-Hispanic black | 0.91 (0.62-1.35) | 0.90 (0.60-1.34) |
Hispanic | 1.16 (0.90-1.51) | 1.13 (0.87-1.49) |
Other | 1.14 (0.85-1.54) | 1.12 (0.83-1.52) |
Living area | ||
Counties in metropolitan areas of 1 million persons | 1 (Reference) | 1 (Reference) |
Counties in metropolitan areas of 250000 to 1 million persons | 1.26 (0.99-1.60) | 1.26 (0.99-1.61) |
Counties in metropolitan areas of 250000 persons | 0.76 (0.46-1.27) | 0.82 (0.49-1.38) |
Nonmetropolitan counties adjacent to a metropolitan area | 0.79 (0.50-1.26) | 0.80 (0.50-1.29) |
Nonmetropolitan counties not adjacent to a metropolitan area | 1.19 (0.70-2.01) | 1.25 (0.74-2.13) |
Income per year | ||
$ < $45000 | 1 (Reference) | 1 (Reference) |
$45000-54999 | 0.75 (0.43-1.31) | 0.72 (0.41-1.26) |
$55000-64999 | 1.04 (0.59-1.82) | 1.01 (0.57-1.77) |
$65000-74999 | 0.85 (0.48-1.51) | 0.84 (0.47-1.50) |
$75000 + | 0.74 (0.42-1.33) | 0.71 (0.40-1.29) |
Radiation | ||
No | 1 (Reference) | 1 (Reference) |
Yes | 0.66 (0.53-0.83)b | 0.64 (0.51-0.81)b |
Chemotherapy | ||
No | 1 (Reference) | 1 (Reference) |
Yes | 0.63 (0.50-0.79)b | 0.62 (0.50-0.78)b |
Surgery | ||
No | 1 (Reference) | 1 (Reference) |
Yes | 0.53 (0.43-0.66)b | 0.51 (0.41-0.63)b |
- Citation: Bangolo AI, Auda A, Bukasa-Kakamba J, Bhakta N, Dey S, lilhori A, Reddy G, Alqinai B, Sidiqui A, Sekhon I, Khatiashvili B, Abbas I, Kunnel S, Jarri A, Martinez E, Daoud D, Gupta I, Gompa H, Pender S, Aljaberi D, Aljanaahi H, Kunnel SS, Xiao Y, Jung Y, Nagpaul S, Naz A, Mallela T, Maung PM, Khalaf IY, Kim S, Alrestom R, Gajera A, Alkealy H, Kansal D, Dhall S, Satheesha S, Weissman S, Fwelo P. Interaction between tumor stage and age on survival outcomes of patients with anaplastic thyroid cancer. World J Exp Med 2024; 14(3): 93869
- URL: https://www.wjgnet.com/2220-315x/full/v14/i3/93869.htm
- DOI: https://dx.doi.org/10.5493/wjem.v14.i3.93869