Association between acute peripancreatic fluid collections and early readmission in acute pancreatitis: A propensity-matched analysis

Table 3 Clinical outcomes of patients with a primary diagnosis of acute pancreatitis during index hospitalizations, stratified by acute peripancreatic fluid collections on index admission, n (%)

Clinical outcomes	Before matching			After matching
	No acute peripancreatic fluid collections	Acute peripancreatic fluid collections	P value	No acute peripancreatic fluid collections	Acute peripancreatic fluid collections	P value
Total patients	638801	34258		33914	33914
Cholangitis	3814 (0.6)	164 (0.5)	0.005	190 (0.6)	160 (0.5)	0.11
Mechanical ventilation	3309 (0.5)	669 (2.0)	< 0.001	300 (0.9)	626 (1.8)	< 0.001
Nausea	13222 (2.1)	650 (1.9)	0.029	752 (2.2)	641 (1.9)	0.003
Diarrhea	15337 (2.4)	1089 (3.2)	< 0.001	898 (2.6)	1074 (3.2)	< 0.001
Septic shock	5693 (0.9)	1110 (3.2)	< 0.001	451 (1.3)	1057 (3.1)	< 0.001
Portal venous thrombosis	4079 (0.6)	1521 (4.4)	< 0.001	265 (0.8)	1487 (4.4)	< 0.001
Splenic venous thrombosis	3194 (0.5)	818 (2.39)	< 0.001	154 (0.5)	811 (2.4)	< 0.001
ICU level admission	3118 (0.5)	529 (1.5)	< 0.001	284 (0.8)	496 (1.5)	< 0.001
Vasopressor use	772 (0.1)	138 (0.4)	< 0.001	70 (0.2)	130 (0.4)	< 0.001
Acute kidney injury	68459 (10.7)	3843 (11.2)	0.004	4038 (11.9)	3744 (11.0)	< 0.001
New RRT during admission	8545 (1.3)	434 (1.3)	0.27	386 (1.1)	421 (1.2)	0.22
Abdominal pain	3070 (0.5)	124 (0.4)	0.002	159 (0.5)	120 (0.4)	0.019
Jaundice	8149 (1.3)	1024 (3.0)	< 0.001	461 (1.4)	1013 (3.0)	< 0.001
Obstruction of bile duct	35968 (5.6)	2340 (6.8)	< 0.001	2259 (6.7)	2319 (6.8)	0.36
Endoscopic retrograde cholangiography (no intervention)	19309 (3.0)	395 (1.2)	< 0.001	740 (2.2)	390 (1.1)	< 0.001
ERCP biliary with intervention	31525 (4.9)	1150 (3.4)	< 0.001	1339 (3.9)	1134 (3.3)	< 0.001
Endoscopic dilation of ampulla and biliary duct	9456 (1.5)	253 (0.7)	< 0.001	413 (1.2)	249 (0.7)	< 0.001
Endoscopic insertion of stent (tube) into bile duct	9784 (1.5)	751 (2.2)	< 0.001	495 (1.5)	743 (2.2)	< 0.001
Endoscopic removal of stone(s) from biliary tract	19161 (3.0)	388 (1.1)	< 0.001	759 (2.2)	384 (1.1)	< 0.001
Endoscopic biopsy of bile duct	2002 (0.3)	62 (0.2)	< 0.001	99 (0.3)	62 (0.2)	0.004
ERCP pancreatic with intervention	6282 (1.0)	1107 (3.2)	< 0.001	323 (1.0)	1094 (3.2)	< 0.001
Endoscopic insertion of stent (tube) into pancreatic duct	5263 (0.8)	1005 (2.9)	< 0.001	278 (0.8)	993 (2.9)	< 0.001
Endoscopic removal of stone(s) from pancreatic duct	1045 (0.2)	152 (0.4)	< 0.001	64 (0.2)	150 (0.4)	< 0.001
Endoscopic dilation of pancreatic duct	583 (0.1)	51 (0.1)	< 0.001	28 (0.1)	50 (0.1)	0.013

RRT: Renal replacement therapy; ERCP: Endoscopic retrograde cholangiopancreatography.