Hepatic and renal effects of oral stingless bee honey in a streptozotocin-induced diabetic rat model

Figure 2 H&E staining of kidney tissue samples on day 13. A: Tissue sample for the non-diabetic control group; B: Untreated (UNT) diabetic group; C: Stingless bee honey (SBH) treatment group; D: Metformin (MET) treatment group; E: Stingless bee honey plus metformin (SBME) treatment group. The UNT group showed an increase in glomerular cellularity and tubular hydropic changes. The MET and SBME groups showed high cellularity and mesangial matrix expansion. The SBH group showed a decrease in hydropic changes and mild cellularity of the glomerulus (H&E staining, 40 ×). G: Glomerulus; CB: Capsule Bowman; T: Tubules; HC: Hydropic changes; IC: Increased cellularity; C: Capillary; M: Mesangial cell; MC: Mild cellularity.