Effects of unilateral superimposed high-frequency jet ventilation on porcine hemodynamics and gas exchange during one-lung flooding

doi:10.5493/wjem.v14.i1.87256

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World Journal of Experimental Medicine

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World J Exp Med. Mar 20, 2024; 14(1): 87256
Published online Mar 20, 2024. doi: 10.5493/wjem.v14.i1.87256

Table 2 Observed gas exchange values. Values are medians with interquartile range for controls, pressure-controlled ventilation and superimposed high-frequency jet ventilation at baseline, one-lung flooding/one-lung ventilation in different animal positions and after one-lung flooding

Variable	Mode	Baseline (TLV)		OLF/OLV		after OLF (TLV)
Variable	Mode	SP	LLP	SP	RLP	SP
PaO₂ (kPa)	CO-group	20.8 (19.7-21.7)	22.0 (21.4-25.1)	20.5 (20.0-21.4)	23.6 (22.0-24.1)	22.5 (21.4- 24.3)
	PCV	20.6 (18.6-22.7)	18.8 (15.3-20.4)^a	17.6 (14.7-19.1)^a	19.8 (18.5-20.3)	22.3 (19.9-23.1)
	SHFJV		14.5 (11.2-20.9)	13.0 (12.6-15.6)^c	13.6 (11.4-17.3)^c
SaO₂ (%)	CO-group	99.7 (99.7-99.8)	99.7 (99.7-99.8)	99.7 (99.7-99.9)	99.7 (99.7-99.9)	99.7 (99.7-99.8)
	PCV	99.7 (99.6-99.8)	99.7 (99.1-99.9)	99.7 (98.8-99.7)	99.7 (99.7-99.7)	99.7 (99.6-99.8)
	SHFJV		98.3 (94.7-99.7)	97.6 (96.4-98.7)^c	97.6 (94.399.2)^c
PaCO₂ (kPa)	CO-group	5.3 (5.0-5.4)	4.9 (4.7-5.0)	4.8 (4.7-4.9)	4.6 (4.54.8)	4.6 (4.3-4.8)
	PCV	5.0 (4.8-6.0)	4.7 (4.3-4.9)^a	4.7 (4.3-5.2)^a	4.7 (4.3-4.9)	4.6 (4.5-4.8)
	SHFJV^b		5.8 (5.5-6.3)^c	5.7 (5.5-6.0)^c	6.2 (5.8-6.8)^c
pH	CO-group	7.46 (7.43-7.49)	7.47 (7.45-7.49)	7.46 (7.43-7.48)	7.44 (7.4-7.46)	7.47 (7.44-7.49)
	PCV	7.46 (7.44-7.48)	7.46 (7.44-7.48)	7.47 (7.45-7.49)	7.46 (7.44-7.48)	7.47 (7.45-7.49)
	SHFJV^b		7.41 (7.39- 7.43)	7.4 (7.39-7.41)	7.38 (7.36-7.39)^c

^aP < 0.05 vs difference from baseline.

^bP < 0.05 vs difference between left lateral position, supine position, and right lateral position.

^cP < 0.05 vs difference between the superimposed high-frequency jet ventilation and pressure-controlled ventilation (PCV). In the control-group, both lungs were ventilated with PCV throughout the experimental period without lung flooding; however, the position change was the same.

SHFJV: Superimposed high-frequency jet ventilation; PCV: Pressure-controlled ventilation; OLF: One-lung flooding; OLV: One-lung ventilation; TLV: Two-lung ventilation; LLP: Left lateral position; SP: Supine position; RLP: Right lateral position; PaO₂: Arterial partial pressure of oxygen; SaO₂: Arterial oxygen saturation; PaCO₂: Arterial partial pressure of carbon dioxide; pH: Hydrogen ion concentration.

Citation: Lesser T, Wolfram F, Braun C, Gottschall R. Effects of unilateral superimposed high-frequency jet ventilation on porcine hemodynamics and gas exchange during one-lung flooding. World J Exp Med 2024; 14(1): 87256
URL: https://www.wjgnet.com/2220-315x/full/v14/i1/87256.htm
DOI: https://dx.doi.org/10.5493/wjem.v14.i1.87256