Copyright
©The Author(s) 2020.
World J Exp Med. Jan 8, 2020; 10(1): 1-9
Published online Jan 8, 2020. doi: 10.5493/wjem.v10.i1.1
Published online Jan 8, 2020. doi: 10.5493/wjem.v10.i1.1
Table 3 Percentage in median, minimum and maximum for transforming growth factor-β1 and bone morphogenetic protein-2 values in cells for chondroid zone
| Chondroid layer | Day | TGF-b1 | P value | BMP-2 | P value | ||
| Control | Alendronate | Control | Alendronate | ||||
| Reserve | 3 | - | - | - | - | 12 (10-14) | P < 0.001 |
| 12 | - | - | - | - | 34 (30-36) | P < 0.001 | |
| Proliferative | 3 | 23.01 (19-26) | 16.27 (14-19) | P = 0.047 | - | 72.21 (70-75) | P < 0.001 |
| 12 | 19.12 (17-23) | 2.33 (0-3) | P < 0.001 | - | 67.43 (66-69) | P < 0.001 | |
| Maturation | 3 | 89.64 (85-93) | 93.07 (91-94) | P = 0.673 | - | 88.61 (86-81) | P < 0.001 |
| 12 | 83 (80-84) | 1.06 (0-1) | P < 0.001 | 13 (12-15) | 94.05 (92-98) | P < 0.001 | |
| Hipertrophic | 3 | 96.35 (94-99) | 97.66 (95-98) | P = 0.772 | 2 (2-3) | 82.17 (80-85) | P < 0.001 |
| 12 | 93.52 (92-95) | 92.31 (90-93) | P = 0.694 | 42 (41-44) | 93.00 (90-95) | P = 0.027 | |
- Citation: Vieira JS, Cunha EJ, de Souza JF, Chaves LHK, de Souza JL, Giovanini AF. Alendronate disturbs femoral growth due to changes during immunolocalization of transforming growth factor-β1 and bone morphogenetic protein-2 in epiphyseal plate. World J Exp Med 2020; 10(1): 1-9
- URL: https://www.wjgnet.com/2220-315x/full/v10/i1/1.htm
- DOI: https://dx.doi.org/10.5493/wjem.v10.i1.1