Statin escape phenomenon: Fact or fiction?

doi:10.5493/wjem.v7.i1.25

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 7, Issue 1

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (7551)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-2) series, Tables (1-2) series.

Item

Count

PDF

479

WORD

466

HTML

3538

Figures (1-2)

180

Tables (1-2)

190

Sum=4853

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

1027

Download

1671

Sum=2698

Feb 20, 2017 (publication date) through Dec 3, 2024

Times Cited of This Article

Times Cited (1)

Journal Information of This Article

Publication Name

World Journal of Experimental Medicine

ISSN

2220-315x

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

World J Exp Med. Feb 20, 2017; 7(1): 25-30
Published online Feb 20, 2017. doi: 10.5493/wjem.v7.i1.25

Table 2 Lipid and metabolic profile of study participants

	Baseline visit	Visit at 6 mo	Most recent visit
TCHOL, mg/dL
Escape group	258 (233-283)	162 (147-174)	182 (170-201)
Non-escape group	259 (235-295)	184 (162-206)^a	172 (154-193)^a
TG, mg/dL
Escape group	117 (89-175)	97 (69-117)	104 (87-129)
Non-escape group	132 (99-181)	104 (83-140)^a	108 (79-130)
HDL-C, mg/dL
Escape group	53 (47-68)	55 (43-64)	54 (48-68)
Non-escape group	53 (46-65)	52 (44-60)	56 (46-62)
LDL-C, mg/dL
Escape group	174 (152-189)	88 (78-97)	103 (96-118)
Non-escape group	177 (152-205)	109 (91-129)^a	94 (79-114)^a
Non-HDL, mg/dL¹
Escape group	204 (181-223)	107 (97-121)	127 (116-143)
Non-escape group	209 (182-241)	132 (115-153)^a	118 (102-137)^a
BMI, kg/m²
Escape group	27.3 (23.5-29.9)	27.2 (23.5-30.1)	27.6 (24-30.2)
Non-escape group	27.9 (25.5-30.6)	28.3 (25.1-30.9)	28.4 (25.5-31.5)
Fasting glucose, mg/dL
Escape group	95 (88-105)	95 (87-129)	95 (88-106)
Non-escape group	93 (87-103)	94 (88-104)	96 (89-106)
HbA1c, %²
Escape group	8.5 (6.7-8.6)	6.6 (5.6-5.9)	6.7 (6.6-7.1)
Non-escape group	8.4 (7.7-10.9)	6.7 (6.3-7.9)	6.9 (6.3-7.6)
MDRD-eGFR, mL/min per 1.73 m²
Escape group	77 (69.6-86.7)	76.6 (67.9-84.8)	76.5 (65.4-81)
Non-escape group	81 (70.7-91.4)	79.7 (69-89.7)	76.9 (65.5-85.7)

Values are expressed as median (IQR). To convert from mg/dL to mmol/L multiply by 0.0555 for glucose, 0.02586 for TC, HDL-C, LDL-C, and 0.01129 for TG.

¹Non-HDL-C levels refer to non-diabetic individuals (n = 164);

²HbA1c values refer to diabetic individuals (n = 17).

^aP < 0.05 for the comparison with the escape group. BMI: Body mass index; MDRD-eGFR: Estimated glomerular filtration rate according to The Modification of Diet in Renal Disease (MDRD) Study equation; HbA1c: Glycated hemoglobin; HDL-C: High-density lipoprotein cholesterol; IQR: Interquartile range; LDL-C: Low-density lipoprotein cholesterol; non-HDL-C: Non-high-density lipoprotein cholesterol; TCHOL: Total cholesterol; TG: Triglycerides.

Citation: Barkas F, Elisaf M, Klouras E, Dimitriou T, Tentolouris N, Liberopoulos E. Statin escape phenomenon: Fact or fiction? World J Exp Med 2017; 7(1): 25-30
URL: https://www.wjgnet.com/2220-315X/full/v7/i1/25.htm
DOI: https://dx.doi.org/10.5493/wjem.v7.i1.25