Lipofuscins prepared by modification of photoreceptor cells via glycation or lipid peroxidation show the similar phototoxicity

Figure 1 Fluorescent products accumulation in weakly oxidised bovine photoreceptor outer segments after 72 h incubation at 37 °C. A: POS fluorescence incubated in the absence of fructose: curve 1 - prior to incubation; curve 2 - after incubation; B: POS fluorescence incubated in the presence of fructose: curve 1 - prior to incubation; curve 2 - after incubation. Fluorescence was measured in 0.1 mol/L K-phosphate buffer, pH 7.6, excitation wavelength - 365 nm.