Are there new approaches for diagnosis, therapy guidance and outcome prediction of sepsis?

Figure 2 Simplified scheme of the impaired immunity during sepsis and the potential use of biomarkers: Initially, the body reacts to infectious stimuli with a proinflammatory immune response. Simultaneously, compensatory mechanisms are initiated to counteract the inflammatory process. The resulting net immune suppression is characterised by an increased risk of opportunistic infections. Beside C-reactive protein and procalcitonin, further biomarkers may be used in diagnosis, therapy-guidance and outcome prediction of sepsis.