Wound healing reaction: A switch from gestation to senescence

Figure 3 Immune or intermediate phase of the post-traumatic acute inflammatory response. Interstitial infiltration by platelets and leukocytes, all of them entrapped in the provisional extracellular matrix (left). Underlying the wound crust (Cr) that is formed later, the leukocytes change their phenotype to promote the resolution of the inflammatory response and wound repair by re-epithelization and scar formation (right). C: Coagulation with fibrin-platelet clot. A: Arterial microcirculation; V: Post-capillary venous circulation; L: Lymphatic circulation.