Ventilator-associated pneumonia in patients with cancer: Impact of multidrug resistant bacteria

Table 5 Univariate and multivariate analysis for 60-d mortality in patients with mechanical ventilation (n = 263)

Characteristics	Univariate			Multivariate
	Alive (n = 147)	Death (n = 116)	P value	OR	P value
Female	79 (53.7)	58 (50)	0.546	-
Male	68 (46.3)	58 (50)
Age < 60 yr	83 (56.5)	72 (62.1)	0.358	-
Age ≥ 60 yr	64 (43.5)	44 (37.9)
Solid tumor	101 (68.7)	74 (63.8)	0.401	-
Hematologic malignancy	46 (31.3)	42 (36.2)
Recent diagnosis, complete or partial remission	85 (57.8)	54 (46.6)	0.069	1	0.237
Progression or relapse	62 (42.2)	62 (53.4)		1.38 (0.81-2.37)
Non-recent chemotherapy	103 (70.1)	61 (52.6)	0.003	1	0.006
Recent chemotherapy	44 (29.9)	55 (47.4)		2.16 (1.24-3.76)
SOFA at ICU admission	8.45 ± 3.45	8.15 ± 3.2	0.471	-
Non-tracheostomy	115 (78.2)	80 (69)	0.088	1	0.01
Required tracheostomy	32 (21.8)	36 (31)		2.52 (1.24-5.13)
Days of ICU length	8 (6, 13)	8 (5, 15)	0.457	-
Days of mechanical ventilation	7 (4, 11)	9 (5, 14)	0.029	1	0.15
				1.04 (1.008-1.07)
Non-VAP	132 (89.8)	99 (85.3)	0.342	-
VAP	15 (10.2)	17 (14.7)

ICU: Intensive care unit; SOFA: Sequential Organ Failure Assessment score; VAP: Ventilator-acquired pneumonia.