Ventilator-associated pneumonia in patients with cancer: Impact of multidrug resistant bacteria

Table 2 Clinical data related with current hospitalization and mechanical ventilation (n = 263)

Characteristic – n (%)	Total (n = 263)	VAP (n = 32)	Non-VAP (n = 231)	P value
Length of hospitalization (d)1	22 (14, 34)	32 (22, 57)	21 (14, 32)	0.0001
Length of ICU stay (d)1	8 (5, 13)	18 (9, 27)	8 (5, 12)	< 0.0001
Causes for MV
Septic shock	91 (34.6)	10 (31.3)	81 (35)	0.843
Post-surgical procedure	42 (16)	8 (25)	34 (14.7)	0.193
Respiratory failure secondary to pneumonia	37 (14)	3 (9.4)	34 (14.7)	0.589
Hypovolemic shock	37 (14)	8 (25)	29 (12.5)	0.09
Neurologic cause	13 (4.9)	0	13 (5.6)	N/A
Lung tumor activity	7 (2.7)	1 (3.1)	6 (2.6)	0.601
Post-CPR	7 (2.7)	1 (3.1)	6 (2.6)	0.601
Acute pulmonary edema	6 (2.3)	0	6 (2.6)	N/A
Malignant central airway obstruction	5 (1.9)	0	5 (2.2)	N/A
Cardiac failure	3 (1.1)	1 (3.1)	2 (0.8)	0.323
Bronchospasm	2 (0.8)	0	2 (0.8)	N/A
Pulmonary embolism	2 (0.8)	0	2 (0.8)	N/A
TRALI	1 (0.4)	0	1 (0.4)	N/A
Other causes	10 (3.8)	0	10 (4.3)	N/A
SOFA at ICU admission2	8.3 ± 3.4	8.7 ± 2.8	8.3 ± 3.4	0.477
Days of mechanical ventilation1	8 (4, 12)	16 (9, 27)	7 (4, 11)	< 0.0001
Tracheostomy	68 (25.9)	19 (59.4)	49 (21.2)	< 0.0001
Re-intubation	27 (10.3)	7 (21.9)	20 (8.7)	0.03
Mortality at 60 d	116 (44.1)	9 (28.1)	72 (31.7)	0.839

¹Median (Interquartile range).

²mean ± SD. CPR: Cardiopulmonary resuscitation; N/A: Not applicable; TRALI: Transfusion-related acute lung injury; ICU: Intensive care unit; SOFA: Sequential Organ Failure Assessment score; MV: Mechanical ventilation; VAP: Ventilator-associated pneumonia.