Experience with hemoadsorption (CytoSorb®) in the management of septic shock patients

Table 4 Change in laboratory and vital parameters (non-survivor group)

Parameters	Pre CytoSorb® therapy	Post CytoSorb® therapy	Percentage change	P value
Urine output (mL/d)	666.48 ± 595.25	493.85 ± 433.11	-25.90	0.0718
CRP (mg/dL)	1175.22 ± 126.60	-	-	-
PCT (ng/dL)	24.91 ± 24.51	48.97 ± 57.57	96.58	0.0766
MAP (mm/Hg)	66.13 ± 9.485	64.31 ± 10.87	-2.75	0.3304
GCS	6.12 ± 4.56	4.27 ± 2.91	-30.23	0.0129a
Leucocytes (cells/mm3)	21.40 ± 26.17	20.25 ± 18.25	-5.34	0.7327
Platelets (cells/mm3)	110.53 ± 50.18	99.67 ± 47.81	-9.83	0.2273
S. Creatinine (mg/dL)	7.01 ± 23.41	5.27 ± 23.19	-24.82	0.0088a
S. Lactate (mmol/L)	4.18 ± 3.23	5.05 ± 3.75	17.2	0.1759
SGOT (U/L)	616.25 ± 1353.71	1418.14 ± 2068	130.12	0.0693
SGPT (U/L)	540.93 ± 1216.70	577.38 ± 945.94	6.74	0.9048
BUN	108.55 ± 92.10	95.02 ± 84.83	-12.46	0.4362
Bilirubin (mg/dL)	5.15 ± 14.19	3.84 ± 4.09	-25.44	0.6543
Sodium (mmol/L)	133.79 ± 26.22	139.51 ± 7.32	4.28	0.1244
Potassium (mmol/L)	4.43 ± 1.03	4.15 ± 1.03	-6.32	0.1392
Albumin (g/L)	3.03 ± 1.07	2.85 ± 0.80	-5.94	0.2988
Arterial pH	7.28 ± 0.14	7.22 ± 0.18	-0.82	0.0438
Bicarbonate	24.52 ± 24.21	22.16 ± 22.19	-9.62	0.6560
PaO2	84.50 ± 48.56	90.42 ± 51.14	7.01	0.5256
PaCO2	40.89 ± 12.20	45.05 ± 33.71	10.17	0.3760
FiO2	69.15 ± 67.74	62.6 ± 28.61	-9.47	0.5016

^aP < 0.05, significant decrease, all values are defined as mean ± SD. Hb: Haemoglobin; SGOT: Serum glutamic oxaloacetic transaminase; SGPT: Serum glutamic-pyruvic transaminase; BUN: Blood urea nitrogen; CRP: C-reactive protein; PCT: Procalcitonin test; MAP: Mean arterial pressure; GCS: Glasgow Coma Scale.