Experience with hemoadsorption (CytoSorb®) in the management of septic shock patients

Table 3 Change in laboratory and vital parameters (survivors)

Parameters	Pre CytoSorb® therapy	Post CytoSorb® therapy	Percentage change	P value
Urine output (mL/d)	551.13 ± 524.60	862.88 ± 682.46	56.56	0.0247a
CRP (mg/dL)	165.68 ± 169.26	120.33 ± 63.72	-27.4	0.6590
PCT (ng/dL)	121.56 ± 421.20	42.81 ± 69.89	-65	0.5859
MAP (mm/Hg)	62.82 ± 9.73	68.23 ± 7.50	8.6	0.1805
GCS	6.26 ± 3.67	8.05 ± 3.92	22.36	0.0417c
Leucocytes (cells/mm3)	15.60 ± 8.56	13.09 ± 6.71	-16.02	0.1484
Platelets (cells/mm3)	123.95 ± 51.42	118.75 ± 48.33	-4.2	0.6425
S. Creatinine (mg/dL)	2.73 ± 1.86	2.27 ± 1.31	-16.84	0.2048
S. Lactate (mmol/L)	3.71 ± 2.30	2.28 ± 0.89	-26.66	0.0159a
SGOT (U/L)	1135.74 ± 2206.67	1078.92 ± 1890.45	-5.00	0.9222
SGPT (U/L)	504.63 ± 876.89	316.59 ± 645.41	-37.26	0.3796
BUN	58.45 ± 36.94	56.67 ± 28.24	-3.05	0.8266
Bilirubin (mg/dL)	3.27 ± 2.67	1.86 ± 1.51	-43.11	0.0565a
Sodium (mmol/L)	136.59 ± 24.49	136.31 ± 24.22	-0.20	0.9615
Potassium (mmol/L)	4.22 ± 0.65	3.75 ± 0.56	-11.14	< 0.0001a
Albumin (g/L)	2.64 ± 0.58	2.65 ± 0.62	0.38	0.9412
Arterial pH	7.33 ± 0.13	7.37 ± 0.13	0.55	0.1727
Bicarbonate	20.32 ± 4.05	22.825 ± 3.86	12.35	0.0060a
PaO2	96.78 ± 41.42	85.88 ± 27.89	-11.26	0.1714
PaCO2	38.46 ± 14.51	38.36 ± 14.53	-0.26	0.9755
FiO2	49.32 ± 18.71	41.95 ± 13.71	-14.94	0.0550

^aP < 0.05, significant decrease;

^cP < 0.05, significant rise. All values are defined as mean ± SD. Hb: Haemoglobin; SGOT: Serum glutamic oxaloacetic transaminase; SGPT: Serum glutamic-pyruvic transaminase; BUN: Blood urea nitrogen; CRP: C-reactive protein; PCT: Procalcitonin test; MAP: Meanarterial pressure; GCS: Glasgow Coma Scale.