Minocycline fails to improve neurologic and histologic outcome after ventricular fibrillation cardiac arrest in rats

Figure 6 Representative samples of neuronal degeneration after 6 min ventricular fibrillation cardiac arrest at 72 h. Blue staining is 4',6-diamidino-2-phenylindole, visualizing neurons, and green staining is Fluoro-Jade C, visualizing degenerating neurons. Hippocampal neuronal loss is visible in the cardiac arrest 1 sector and in hilar region of the dentate gyrus. The inset shows the mid-section of cardiac arrest 1 in closer detail. Marked neuronal degeneration of the medium spiny neurons is seen in the striatum. Selectively vulnerable neuronal loss of Purkinje neurons visualized in the cerebellum. No neurodegeneration is observed in the cortex. Magnification × 10 except the panoramic view of the hippocampus, magnification × 4. The scale bars in the far left and far right lower panels represent 10 µm.