Spectrum of cardiac manifestations and its relationship to outcomes in patients admitted with scrub typhus infection

Table 1 Demographics, symptoms, co-morbidities, and laboratory parameters in patients with and without myocarditis

Characteristic	With myocarditis (n = 10)	No myocarditis (n = 71)	P value
Demographic
Age, mean (SD), yr	56.5 (13.7)	48.4 (16.2)	0.14
Gender (female:male)	41:30:00	5:05	0.64
Illness duration, mean (SD), d	6.8 (3.1)	8.3 (3.0)	0.16
Symptom, n (%)
Fever	10 (100)	71 (100)	1.00
Cough	2 (10)	27 (38)	0.27
Breathlessness	8 (80)	54 (76)	0.78
Altered mental status	3 (30)	12 (16.9)	0.32
Myalgia	5 (50)	25 (35.2)	0.36
Vomiting	3 (30)	19 (27.8)	0.83
Co-morbidity, n (%)
Diabetes	0	16 (22.5)	0.09
Hypertension	1 (10)	14 (19.7)	0.46
Pregnancy	0	5 (7)	0.39
Coronary artery disease	0	2 (2.8)	0.59
Smoking	1 (10)	2 (2.8)	0.26
Laboratory parameter, mean (SD)
Hemoglobin, g %	12.9 (3.6)	11.3 (2.2)	0.06
Total white cell count, cmm	11360 (5484)	10649.3 (4879)	0.67
Platelets, cmm	47400 (36039)	65376 (62668)	0.38
Creatinine, mg %	1.6 (1.1)	1.7 (1.5)	0.76
Total bilirubin, mg %	1.7 (1.1)	2.1 (2.0)	0.49
Direct bilirubin, mg %	1.3 (1.0)	1.6 (1.7)	0.55
Serum albumin, mg %	2.3 (0.7)	2.6 (0.5)	0.20
AST, U/L	173 (143)	142 (92)	0.37
ALT, U/L	69 (53)	71.7 (51)	0.88
Alkaline phosphatase, U/L	196 (105)	203 (108)	0.84
SOFA score	10.6 (2.8)	8.7 (4.0)	0.16
APACHE II score	17.1 (8.3)	15.5 (6.8)	0.50

n: Number of patients; SD: Standard deviation; AST: Serum aspartate aminotransferase; ALT: Serum alanine transaminase; SOFA: Sequential Organ Failure Assessment; APACHE: Acute Physiology and Chronic Health Evaluation; ICU: Intensive care unit.