Retrospective Study
Copyright ©The Author(s) 2017.
World J Crit Care Med. Nov 4, 2017; 6(4): 179-184
Published online Nov 4, 2017. doi: 10.5492/wjccm.v6.i4.179
Table 2 Average doses, sedation times and adverse events
VariableOverall (n = 458)Propofol only (n = 337)Propofol ketamine (n = 121)P value
Propofol dose (mg/kg)4.1 (2.7, 5.6)4.2 (2.7, 5.6)3.7 (2.8, 5.2)0.3
Procedure time (min)10 (6, 15)10 (7, 12)10 (5, 15)0.3
Recovery time (min)25 (20, 30)25 (20, 30)25 (20, 35)0.63
Time to discharge (min)35 (30, 43)35 (30, 40)35 (30, 45)0.31
Respiratory events
Prophylactic use of O2 supplementation prior to bronchoscopy, n (%)423 (92.4)311 (92.3)112 (92.6)0.92
Hypoxemia, n (%)38 (8.3)29 (8.6)9 (7.4)0.69
BMV/significant desaturation1, n (%)0.58
Neither413 (91.2)302 (90.7)111 (92.5)
BMV + significant desaturation23 (5.1)16 (4.8)7 (5.8)
Significant desaturation only16 (3.5)14 (4.2)2 (1.7)
BMV use only1 (0.2)1 (0.3)0 (0)
Cardiac events
Start MBP77.7 (70.3, 86.7)78.3 (71.3, 86.3)76.3 (68.0, 88.7)0.58
End MBP70.3 (63.0, 78.7)71.0 (64.0, 79.3)68.7 (61.7, 76.3)0.04
Difference in MBP-7.5 (-17.0, 2.0)-6.7 (-16.0, 2.7)-8.7 (-19.0, 0.7)0.12
% Change MBP from start of procedure-9.8 (-20.0, 3.0)-9.2 (-18.8, 4.3)-10.5 (-22.8, 0.7)0.12
Blood pressure drop more than 20% from the baseline (hypotension)108 (23.6%)76 (22.6%)32 (26.4%)0.4