Comparison of inhaled milrinone, nitric oxide and prostacyclin in acute respiratory distress syndrome

Table 2 Hemodynamic parameter variations (n = 15)

	iNO	Epoprostenol	Milrinone	Milrinone + NO
MAP (mmHg)	-2.0 (11.0)	1.0 (8.0)	3.0 (6.0)	3.0 (7.0)
HR (bpm)	-2.0 (6.0)	0.0 (4.0)	0.0 (4.0)	0.0 (6.0)1
CVP (mmHg)	0.0 (1.4)	0.0 (4.0)	0.0 (1.0)	-1.0 (2.0)
PAOP (mmHg)	0.0 (3.0)	1.0 (4.0)	0.0(2.0)	-1.0(3.0)
mPAP (mmHg)	-2.0 (4.0)	-1.0 (3.0)	0.0 (3.0)	-2.0 (3.0)1
CI (L/min per square metre)	0.1 (0.6)	0.0 (0.7)	0.6 (0.9)	-0.1 (0.4)
iPVR	-30.6 (130.9)	-51.7 (165.2)	-9.4 (103.1)	0.0 (91.2)

¹No hemodynamic variation reached statistical significance (P > 0.1 for any value) except for the median mPAP variations in the Milrinone + NO group (P = 0.47). MAP: Mean arterial pressure; HR: Heart rate; CVP: Central venous pressure; PAOP: Pulmonary artery occlusion pressure; mPAP: Mean pulmonary arterial pressure; CI: Cardiac index; iPVR: Indexed pulmonary vascular resistance; iNO: Inhaled nitric oxide.