Timing, method and discontinuation of hydrocortisone administration for septic shock patients

Table 3 Univariate and multivariate logistic regression analysis for relevant factors associated with new-onset hypokalemia

Variable	Univariate		P value	Multivariate	P value
	NO-HK (n = 30)	No NO-HK (n = 29)		Adjusted OR (95%CI)
Bolus hydrocortisone, n (%)	12 (40)	20 (69)	0.02	8.5 (1.2-59.9)	0.03
Hydrocortisone taper, n (%)	17 (77.3)	6 (30)	0.002	10.6 (1.5-73.3)	0.01
AKI, n (%)	13 (43.3)	18 (62.1)	0.08	0.1 (0.01-0.8)	0.03
Diuretic use, n (%)	20 (66.7)	10 (34.5)	0.01	6.3 (0.95-42.0)	0.05

Goodness-of-fit (Hosmer-Lemeshow). χ² = 5.52, P = 0.59; AUC, 0.88 (0.74-0.95), P = 0.0001. AKI: Acute kidney injury; HK: Hypokalemia; OR: Odds ratio.