Risk factors for mortality in postoperative peritonitis in critically ill patients

Table 3 Antimicrobial therapies and medical complications n (%)

	Total (n = 201)	Non-survivors (n = 63)	Survivors (n = 138)	P
Antibiotic prophylaxis for the first surgery	165 (82)	53 (84)	112 (81)	0.38
Antimicrobial treatment prior to the first reintervention	132 (66)	40 (63)	93 (67)	0.564
Empirical antibiotic therapy for POP effective against Enterococcus spp.	104 (52)	35 (56)	69 (50)	0.466
Change in empirical antimicrobial POP treatment	130 (65)	33 (52)	97 (70)	0.005
Escalation	60 (46)	20 (32)	40 (29)
De-escalation	70 (54)	13 (21)	57 (41)
Medical complications				0.001
Septic shock	125 (62)	58 (92)	67 (49)
Acute renal failure	79 (39)	39 (62)	40 (29)
ARDS	54 (27)	28 (44)	26 (19)
Lengths of stay, d
ICU	17 ± 17	17 ± 18	17 ± 17	0.2
Hospital	48 ± 44	31 ± 27	57 ± 48	< 0.001

Data are expressed as the mean ± SD or as the number of patients (percentages). POP: Postoperative peritonitis; ARDS: Acute respiratory distress syndrome; ICU: Intensive care unit.