Cannabis use disorder and severe sepsis outcomes in cancer patients: Insights from a national inpatient sample

Table 3 Multivariable regression analysis of primary outcomes comparing cancer patients admitted for severe sepsis with vs without cannabis use disorder

Events	Adjusted OR	95%CI	P value
MACCE	0.86	0.74-1.01	0.059
All-cause in-hospital mortality	0.83	0.7-0.97	0.022
Acute myocardial infarction	1.03	0.77-1.37	0.84
Cardiac arrest, ventricular fibrillationand ventricular flutter	1.14	0.51-2.52	0.754
Acute ischemic stroke	0.89	0.53-1.5	0.671
Respiratory failure	0.8	0.69-0.92	0.002

Values are as adjusted odds ratios. Accompanying 95% confidence intervals and P values for significance. Factors adjusted for are age, sex, race, median household income, payer type, elective status, hospital bed size, hospital location and teaching status, hospital region, acquired immunodeficiency syndrome, autoimmune conditions, depression, diabetes with and without chronic complications, hypertension (complicated and uncomplicated), hyperlipidemia, chronic pulmonary disease, obesity, peripheral vascular disease, hypothyroidism, valvular disease, drug abuse, alcohol abuse, smoker status, cocaine abuse, prior myocardial infarction, prior transient ischemic attack or stroke, and prior cancer history. OR; Odds ratio; CI: Confidence interval; MACCE: Major adverse cardiac and cerebrovascular events.