Cannabis use disorder and severe sepsis outcomes in cancer patients: Insights from a national inpatient sample

Table 2 Primary and secondary in-hospital outcomes among cancer patients admitted for severe sepsis with vs without cannabis use disorder

Outcomes	CUD(-) (n = 738575)	CUD(+) (n = 4945)	P value
MACCE	36	28.4	< 0.001
All-cause in-hospital mortality	30.5	23.4	< 0.001
Acute myocardial infarction	7.2	5.5	< 0.001
Cardiac arrest, ventricular fibrillationand ventricular flutter	0.6	0.8	0.038
Acute ischemic stroke	2	1.7	0.207
Respiratory failure	50.9	48.6	0.002
Disposition of patient1	-	-	< 0.001
Routine	18.8	31.5	-
Transfer to short term facility	3.4	3	-
Other transfers (SNF, ICF etc.)	25.8	17.8	-
Home healthcare	21	21.8	-
Length of stay (median, days)	7	7	0.034
Total cost of hospitalization (median, USD)	86615	94574	< 0.001

¹Disposition is at time of discharge and subject to state-specific differences in classification, https://hcup-us.ahrq.gov/db/vars/disp/nisnote.jsp

Values are in percentages unless stated. Accompanying 95% confidence intervals and P values for significance. CUD: Cannabis use disorder; MACCE: Major adverse cardiac and cerebrovascular events; SNF: Skilled nursing facility, ICF: Intermediate care facility; USD: United States dollar.