Clinical prediction scores predicting weaning failure from invasive mechanical ventilation: Role and limitations

Table 4 Criteria to assess for readiness to wean

Clinical criteria	Objective criteria
Primary disease for which patient needed IMV is improving; good cough reflex; absence of secretions	Respiratory; SaO2 > 90% with FiO2 < 0.4 (Pf > 150), PEEP < 8 cm H2O; RR < 35/min; MIP < 20-25 cm H2O; Vt > 5 mL/kg on SBT; VC > 10 mL/kg; No acidosis. Cardiovascular; HR < 140/min; SBP 90-160 mmHg with minimal to no vasopressors; neurological; conscious or adequate mental status with good airway reflexes

FiO₂: Fraction of inspired oxygen; IMV: Invasive mechanical ventilation; SBT: Spontaneous breathing trial; HR: Heart rate; MIP: Maximum inspiratory pressure; PEEP: Positive end-expiratory pressure; RR: Respiratory rate; SaO₂: Oxygen saturation of arterial blood; SBP: Systolic blood pressure; Vt: Tidal volume; VC: Vital capacity.