Outcome of COVID-19 infection in patients on antihypertensives: A cross-sectional study

Table 3 Laboratory parameters at admission

Parameter	Total population, n = 260	Nonhypertensive, n = 60	ACEI/ARB, n = 62	Calcium channel blockers, n = 64	ACEI/ARB + CCB, n = 60	Beta-blockers, n = 14	P value
Hemoglobin in gm/dL	12.95 (2.0)	13.47 (5.4)	12.94 (1.9)	12.45 (2.1)	12.9 (1.7)	13.36 (2.6)	0.077
Total leukocyte count as /cu mm	7683.8 (3991.9)	6993.83 (3576.08)	7755.32 (3712.07)	8126.41 (4186.3)	7739.33 (4604.2)	8062.86 (3205.9)	0.606
Neutrophil/lymphocyte ratio (IQR)	1-6	1-3	2-6.25	1.25-6	2-9.5	1-15.255	< 0.001
Platelets as /cu mm	237765.38 (90546.23)	235183.33 (78058.10)	249467.74 (98418.26)	233046.88 (96977.24)	239116.67 (88116.08)	212785.71 (89160.33)	0.677
ESR in mm/h (IQR)	9-38	7-28.5	8-38.5	10.5-39.5	12.5-48.54	10.5-40.2	0.007
Serumhs-CRP in mg/dL (IQR)	3-67	1.25-15	8.5-88.2	6-85.2	3-89.54	13-85.7	< 0.001
Plasma glucose at admission in mg/dL	135.82 (65.1)	104.9 (48.5)	162 (63.9)2	126.28 (59.0)	148.9 (60.3)	139.43 (53.8)	< 0.001
Blood urea in mg/dL (IQR)	21-38	19-291	21-37.25	23.25-43	21-43.5	18.5-43.2	0.002
Serum creatinine in mg/dL	1.19 (0.78)	1.1 (0.54)	1.2 (1.05)	1.2 (0.64)	1.2 (0.4)	1.4 (1.6)	0.164
Serum interleukin 6 in pg/mL (IQR)	20-188.2	68.5-200	13.2-118.52	17.2-219.2	16.7-159.5	10.7-155.7	0.004
Serum ferritin in ng/mL (IQR)	67.25-449.5	31.25-242.5	116-459	76.5-660.253	46.5-541	46.5-520.5	0.017
D-Dimer in μg/mL (IQR)	0-2	0-1	0-3	0-2	0-2	0-1.2	0.43
Serum lactate dehydrogenase in IU/L (IQR)	179-321	180.2-256.7	170-330.2	186.7-318.5	175-359.7	187.2-347.7	0.751
Serum creatine kinase in IU/L (IQR)	45.25-107.7	49-109.5	45-98.2	39.75-118	48-108	49.75-109.7	0.964
Serum procalcitonin in ng/mL	0.16 (0.44)	0.12 (0.32)	0.26 (0.72)	0.13 (0.4)	0.13 (0.3)	0.21 (0.4)	0.695

¹Significant difference between the nonhypertensive group and others.

²Significant difference between the ACEI/ARB group and others.

³Significant difference between the CCB group and others.

⁴Significant difference between the ACEI/ARB + CCB group and others.

⁵Significant difference between the beta-blocker group and others.

Data are mean ± standard deviation unless indicated otherwise. ACEI: Angiotensin-converting enzyme inhibitor; ARB: Angiotensin receptor blocker; CCB: Calcium channel blocker; ESR: Erythrocyte sedimentation rate; hs-CRP: High-sensitivity C-reactive protein; IQR: Interquartile range.