Early clinical outcomes of two regimens of prophylactic antibiotics in cardiac surgical patients with delayed sternal closure

Table 1 Baseline characteristics among the studied population

Variable	All patients, n = 53	Narrow-spectrum antibiotics, n = 12	Broad-spectrum antibiotics, n = 41	P value
Demographics
Age in yr	59.0 ± 12.1	60.0 ± 13.4	58.7 ± 11.8	0.366
BMI in kg/m2	26.7 ± 4.9 (N = 52)	25.7 ± 3.7 (n = 12)	26.7 ± 5.2 (n = 40)	0.227
Sex				0.175
Male	45/53 (85.0)	12	33
Female		0	8
Ethnicity				0.011
African	3/53 (5.7)	3	0
Arab	24/53 (45.3)	4	11
Asian from Indian subcontinent	20/53 (37.7)	3	17
Asia	4/53 (7.5)	0	4
Western	2/53 (3.8)	1	1
Smoking status				0.402
Non-smoker	23/51 (45.1)	3	20
Smoker	7/51 (13.7)	1	6
Ex-smoker	21/51 (41.2)	6	15
Comorbidities
Hypertension	28/51 (54.9)	4	24	0.086
Diabetes				0.305
Type II	16/53 (30.2)	4	12
Type I	7/53 (13.2)	0	7
COPD	2/52 (3.8)	0	2	1.00
CKD	8/53 (15.1)	1	7	0.665
On dialysis	2/53 (3.8)	0	2	1.00
PVD	2/53 (3.8)	0	2	1.00
Statin use	24/52 (46.2)	5	19	0.722
ECHO
LVEF as %	43.4 ± 16.9	45.8 ± 12.9	42.7 ± 18.0	0.578
LVEF groups				0.309
Good, > 50%	23/53 (43.4)	4	19
Moderate, 31%-50%	16/53 (30.2)	6	10
Poor, 21%-30%	10/53 (18.9)	2	8
Very poor, ≤ 20%	4/53 (7.5)	0	4

Data are total N/subset n (%) or mean ± standard deviation. BMI: Body mass index; CKD: Chronic kidney disease; COPD: Chronic obstructive pulmonary disease; ECHO: Echocardiography; LVEF: Left ventricular ejection fraction; PVD: Peripheral vascular disease.