Steroids in acute respiratory distress syndrome: A panacea or still a puzzle?

Table 7 Suggested steroids in acute respiratory distress syndrome based on evidence until now

Category of ARDS	Steroid details
COVID-19 ARDS	Dexamethasone, 6 mg IV, start after 1 wk of symptom onset, duration for 10 d or until hospital discharge (if sooner)
Non-COVID-19 ARDS	No high-quality evidence available; hydrocortisone, 200 mg per day, start within 24 h of onset of severe CAP, duration for 8 d or 14 d (based on level of improvement at day 4)
ARDS with septic shock	Hydrocortisone, 200 mg per day, start if need of vasopressors or inotropes for a minimum of 4 h, duration for a maximum of 7 d or until ICU discharge or death

COVID-19: Coronavirus disease 2019; ARDS: Acute respiratory distress syndrome; CAP: Community-acquired pneumonia; ICU: Intensive care unit.