Predictive value of thrombocytopenia for bloodstream infection in patients with sepsis and septic shock

Table 2 Patient laboratory characteristics

Characteristic	All patients (n = 218)	Blood culture results		P value
		Negative or contamination (n = 133)	Positive with pathogen (n = 85)
PCT (ng/mL)	6.9 (1.1-32.1)	2.85 (0.4-16.6)	16.8 (4.1-112.3)	< 0.001
CRP (mg/mL)	113.3 (47.9-174.3)	99.4 (41.1-168.3)	128.1 (68.5-189.7)	0.047
WBC (× 109/L)	12.3 (8.1–17.8)	11.7 (8.8–16.8)	13.1 (7.5–21.7)	0.404
Neutrophils (%)	90.1 (82.5-93.5)	88.9 (83.4-92.3)	92.2 (82.3-94.7)	0.029
Haemoglobin (g/L)	109.6 ± 23.8	109.9 ± 24	109.2 ± 23.6	0.824
HBA1C	5.9 (5.4-7.2)	6.0 (5.6-7.1)	5.8 (5.3-8.6)	0.7
PT (s)	14.4 (12.7-16.7)	13.9 (12.7-15.7)	15.5 (12.7-17.5)	0.012
APTT (s)	34.5 (30.2-41.5)	33.3 (29.6-38.0)	37.2 (30.2-44.8)	0.005
Fib (g/L)	3.94 (3.0-4.97)	3.95 (3.19-5.26)	3.93 (2.85-4.87)	0.344
D-dimer (μg/mL)	6.37 (2.62-12.34)	5.33 (2.19-10.94)	8.06 (3.93-13.81)	0.02
Alanine aminotransferase (U/L)	31.8 (18–61.2)	24.2 (14.8–47.5)	43.4 (23.1–113.9)	< 0.001
Aspartate aminotransferase (U/L)	46.2 (29.6–87.1)	37.9 (25.8–70)	67.2 (35.2–170.4)	< 0.001
Total bilirubin (μmol/L)	15.6 (9.1–29.1)	13.5 (8.9–23.7)	20.6 (10.7–49)	0.009
Serum albumin (g/L)	28.8 (24.4-31.7)	28 (24.2-32.2)	29.4 (25-31.5)	0.444
BUN (mmol/L)	9.9 (6.0–15.3)	9.2 (5.9–14.2)	10.8 (6.2–15.9)	0.147
Cr (μmol/L)	99.6 (67.3–180)	89.1 (62.4–146)	134.5 (84.7–221)	0.001

PCT: Procalcitonin; CRP: C-reactive protein; WBC: White blood cell; HBAIC: Glycosylated haemoglobin; PT: Prothrombin time; APTT: Activated partial thromboplastin time; Fib: Fibrinogen; BUN: Blood urea nitrogen; Cr: Creatinine.