Delayed inflammatory pulmonary syndrome: A distinct clinical entity in the spectrum of inflammatory syndromes in COVID-19 infection?

Figure 2 Representative Cross sectional computed tomography and plain radiograph images of patients with Delayed Inflammatory Pulmonary Syndrome. A: High resolution transverse computed tomography (CT) sections of patient 4, showing the evolution of infiltrates from day -2 of Delayed Inflammatory Pulmonary Syndrome (DIPS) (A1) till day +15 (A2). The diffuse ground glass opacities seen in A1 have reduced, while the areas of consolidation (marked with yellow arrows) have increased slightly, along with features of tractional bronchiectasis, suggestive of coronavirus disease (COVID) sequelae. The overall improvement in clinical status from A1 to A2 could suggest that the ground glass opacities were part of the inflammatory changes in the lungs and responded to immunomodulation; B: Representative plain radiographs (portable) of patient 1 showing the evolution of infiltrates from day -7 of DIPS (B1) till day 0 (B2), followed by improvement on day +1 (B3), after the initiation of glucocorticoids; C: Representative chest radiograph and coronal high resolution CT sections on day -26 (C1, taken in the index admission for mild COVID on day 10 of symptom onset) before the onset of DIPS, significant increase in diffuse ground glass opacities on day 0 of DIPS (C2), followed by improvement on day +1 of DIPS (C3).