Role of cerebrospinal fluid lactate in diagnosing meningitis in critically ill patients

doi:10.5492/wjccm.v12.i1.1

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Jan 9, 2023 (publication date) through Nov 30, 2024

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World Journal of Critical Care Medicine

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2220-3141

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Crit Care Med. Jan 9, 2023; 12(1): 1-9
Published online Jan 9, 2023. doi: 10.5492/wjccm.v12.i1.1

Table 2 Comparison of cerebrospinal fluid analysis between meningitis and non-meningitis groups

CSF parameters	Meningitis group (n = 23)	Non-meningitis group (n = 48)	P value
TLC (mean ± SD)	1223.4 ± 2611	8.1 ± 12.6	< 0.001^a
Protein (mean ± SD)	177.1 ± 204.2	69.3 ± 61.5	0.002^a
Sugar mg/dL (mean ± SD)	90.1 ± 98.4	102.1 ± 41	0.011^a
Lactate levels mg/dL (mean ± SD)	60 ± 43.9	23.6 ± 11.1	< 0.001^a
Lactate levels mmol/L (mean ± SD)	6.6 ± 4.8	2.6 ± 1.2	< 0.001^a
Positive CSF cultures	17 (74)	0 (0)	< 0.001^a
Positive meningo-encephalitis panel	7 (30)	0 (0)	0.001^a
Positive CSF cultures or meningo-encephalitis panel	23 (100)	0 (0)	< 0.001^a

^aP value statistically significant.

CSF: Cerebrospinal fluid; SD: Standard deviation.

Citation: Yadav D, Singh O, Juneja D, Goel A, Kataria S, Beniwal A. Role of cerebrospinal fluid lactate in diagnosing meningitis in critically ill patients. World J Crit Care Med 2023; 12(1): 1-9
URL: https://www.wjgnet.com/2220-3141/full/v12/i1/1.htm
DOI: https://dx.doi.org/10.5492/wjccm.v12.i1.1