Postoperative complications and critical care management after cytoreduction surgery and hyperthermic intraperitoneal chemotherapy: A systematic review of the literature

doi:10.5492/wjccm.v11.i6.375

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World Journal of Critical Care Medicine

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World J Crit Care Med. Nov 9, 2022; 11(6): 375-386
Published online Nov 9, 2022. doi: 10.5492/wjccm.v11.i6.375

Table 3 Systemic toxicities due to chemotherapy

Ref.	HIPEC drugs	EPIC	Nephrotoxicity, %	Haematological toxicity, %
Glehen et al[36], 2010	MMC + CDDP/Ox + 5FU/leucovorin	MMC+5FU	1	13.3
Bakrin et al[1], 2012	CDDP + MMC/DX			3
Baratti et al[17], 2012	CDDP + MMC/DX		5.4	5.9
Bakrin et al[16], 2013	CDDP/MMC/DX		11	11
Canda et al[27], 2013	CDDP + /MMC		25.8	19.8
Jafari et a^l[15], 2014	NA		3.7	0

EPIC: Early postoperative chemotherapy; HIPEC: Hyperthermic intraperitoneal chemotherapy; MMC: Mitomycin-C; CDDP-Cisplatin, 5FU” % flurouracil; Ox: Oxaloplatin; Dx: Adriamycin.

Citation: Wajekar AS, Solanki SL, Patil VP. Postoperative complications and critical care management after cytoreduction surgery and hyperthermic intraperitoneal chemotherapy: A systematic review of the literature. World J Crit Care Med 2022; 11(6): 375-386
URL: https://www.wjgnet.com/2220-3141/full/v11/i6/375.htm
DOI: https://dx.doi.org/10.5492/wjccm.v11.i6.375