Observational Study
Copyright ©The Author(s) 2022.
World J Crit Care Med. Jul 9, 2022; 11(4): 246-254
Published online Jul 9, 2022. doi: 10.5492/wjccm.v11.i4.246
Table 1 Demographic and primary clinical characteristics in the Sepsis, vasoplegic shock and septic shock 3.0 groups
IQR
Sepsis
Vasoplegic shock
Septic shock 3.0
Total
P
(n = 51)(n = 26)(n = 41)(n = 118)
Age, years (mean ± SD)59.51 ± 13.761.9 ± 12.968.7 ± 10.663.3 ± 13.10.005
Gender, males (n)381930870.986
Body mass index (mean ± SD)27.56 ± 4.4429.67 ± 6.727.9 ± 4.128.2 ± 4.90.591
SOFA at admission [mean (IQR)]3.04 (2; 4)5.88 (3; 8)7.14 (4; 9)5.13 (2; 7.8)< 0.001
Mechanical ventilation (n)5263768< 0.001
Length of mechanical ventilation, d [mean (IQR)]1.06 (0; 2)12.5 (4.75;17)19.3 (7.5; 28)9.9 (0; 17.3)< 0.001
Minimum paO2/FiO2 registered (mean ± SD)181.9 ± 82.1104.9 ± 69.292 ± 64.5133.7 ± 84.4< 0.001
Ventilation in prone position, h [mean (IQR)]4.55 (3; 5.1)70.2 (0; 134.8)129.1 (0; 187.5)62.3 (0; 96)< 0.001
Length of neuromuscular blockade, d [mean (IQR)]0 (0; 0)6.5 (2; 9.3)8.3 (3; 16.5)4.9 (0; 8.3)< 0.001
Vasopressor support (n)0264167< 0.001
Minimum blood pressure registered, mmHg (mean ± SD)60.1 ± 11.352.8 ± 8.148.7 ± 9.554.5 ± 11.2< 0.001
Maximum dose of vasopressor therapy, µg/kg (mean ± SD)-22.5 ± 18.830.5 ± 16.315.6 ± 18.9< 0.001
Maximum serum lactate level, mg/dL (mean ± SD)1.64 ± 0.561.39 ± 0.353.88 ± 2.82.36 ± 2< 0.001
Maximum serum troponin level, ng/mL [mean (IQR)]22.04 (6; 25)103.4 (17.75; 124.8)129.7 (40; 166.5)77.4 (13; 93)< 0.001
Minimum serum hemoglobin level, g/dL (mean ± SD)11.4 ± 2.19.3 ± 28.1 ± 1.8 9.8 ± 2.5< 0.001
Maximum serum C-reactive protein, mg/dL (mean ± SD)18.2 ± 9.4530.2 ± 9.931.9 ± 8.825.6 ± 11.3< 0.001
Maximum serum Procalcitonin, ng/mL [mean (IQR)]2.29 (0.1; 0.8)6.65 (0.4; 5.9)10.4 (1.1; 12.4)6.23 (0.3; 5.9)< 0.001
Maximum creatinine level registered, mg/dL [mean (IQR)]1.68 (0.82; 1.2)2.66 (0.83; 2.54)3 (1.3; 3.8)2.36 (0.9; 2.8)< 0.001
Renal support therapy (n)4 (8%)7 (3%)20 (49%)31 (26%)< 0.001
Secondary infections, per patient [mean (IQR)]0.16 (0; 0)0.63 (0; 1)1.1 (0; 1.5)0.55 (0; 1)< 0.001
Remdesivir (n, %)22 (43%)13 (50%)20 (49%)55 (47%)0.8
Corticosteroid therapy (n)14 (27%)4 (15%)20 (49%)38 (32%)0.01