Plasma D-dimer level in early and late-onset neonatal sepsis

Table 1 The control and patients' demographic and clinical and laboratory data

		Control group (n = 30)	EOS group (n = 30)	LOS group (n = 30)	t/Z	P value
Age (mean ± SD, d)		2.10 ± 0.8	2.47 ± 0.57	12.47 ± 4.03	147.024	0.001
Weight (mean ± SD, g)		2.98 ± 0.4	2.85 ± 0.41	2.95 ± 0.3	0.895	NS
Male: Female		0.9:1	0.87: 1	1.5:1	0.356	NS
% of cesarean section		23 (76.7%)	22 (73.3%)	21 (70%)	0.381	NS
PROM		0	6 (20%)	0
Risk factors (invasive procedure)	UVC	0	4 (13.3%)	0		0.001
	ETT	0	5 (16.7%)	4 (13.3%)		0.001
	UVC + ETT	0	7 (23.3%)	13 (43.3%)		0.001
	None	100%	14 (46.7%)	13 (43.3%)		0.001
Respiratory distress		0	27 (90%)	23 (77%)	1.920	NS
Apnea		0	3 (10%)	3 (10%)	FE	NS
Cyanosis		0	10 (33.3%)	14 (46.7%)	1.111	NS
Positive Gerdes score (≥ 2)		0	22 (73.3%)	19 (63.3 %)	38.258	0.001
Thrombocytopenia		2 (6.7%)	22 (73%)	12 (40%)	6.787	0.009
CRP (mg/dL)		4 ± 2	57.53 ± 38.82	65.47 ± 39.62	0.783	NS
D-dimer (mg/L)		0.60 ± 0.70	1.48 ± 1.44	2.27 ± 1.86	10.512	0.001
Hospital duration		0	21.6 ± 10	22 ± 9	0.051	NS
Mortality		0	9 (30%)	11 (36.7%)	0.300	NS

ETT: Endotracheal intubation; PROM: Premature rupture of membranes; UVC: Umbilical vein catheterization; NS: Not significant.