Observational Study
Copyright ©The Author(s) 2022.
World J Crit Care Med. Mar 9, 2022; 11(2): 102-111
Published online Mar 9, 2022. doi: 10.5492/wjccm.v11.i2.102
Table 2 Comparison of outcomes according to latitude and altitudes
Study outcomes
Latitude
Altitude
Unadjusted
Adjusted
Unadjusted
Adjusted
Estimate95%CIP value Estimate95%CIP value Estimate95%CIP value Estimate95%CIP value
28 d mortality1.39(1.04, 1.86)0.0251.32(1.00, 1.74)0.051RCS, P value non-linearity ≤ 0.001, P value overall association = 0.001RCS, P value non-linearity = 0.049, P value overall association = 0.017
Hospital-free days-1.47(-2.60, -0.33)0.011-1.07(-2.13, -0.01)0.0500.14(-0.37, 0.64)0.5870.10(0.37, 0.56)0.683
For the altitude points of 75 MASL, 125 MASL, 400 MASL, and 600 MASL, compared to the reference altitude of 148 MASL; the adjusted odds ratios and 95%CIs regarding 28 d mortality were 0.96 (0.62,1.47), 1.04 (0.92,1.19), 0.49 (0.22, 0.90), and 0.51 (0.27, 0.98), respectively. CI: Confidence interval; ICU: Intensive care unit; MASL: Meters above sea level; RCS: Restricted cubic spline.
  • Citation: Tekin A, Qamar S, Singh R, Bansal V, Sharma M, LeMahieu AM, Hanson AC, Schulte PJ, Bogojevic M, Deo N, Zec S, Valencia Morales DJ, Belden KA, Heavner SF, Kaufman M, Cheruku S, Danesh VC, Banner-Goodspeed VM, St Hill CA, Christie AB, Khan SA, Retford L, Boman K, Kumar VK, O'Horo JC, Domecq JP, Walkey AJ, Gajic O, Kashyap R, Surani S, The Society of Critical Care Medicine (SCCM) Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS): COVID-19 Registry Investigator Group. Association of latitude and altitude with adverse outcomes in patients with COVID-19: The VIRUS registry. World J Crit Care Med 2022; 11(2): 102-111
  • URL: https://www.wjgnet.com/2220-3141/full/v11/i2/102.htm
  • DOI: https://dx.doi.org/10.5492/wjccm.v11.i2.102