Efficacy of remdesivir for hospitalized COVID-19 patients with end stage renal disease

Table 3 Group mean comparisons

D dimers	Diabetes	Condition	Mean	Z	P value	Cohen's d
Outcome: Max O2
High	Yes	Remdesivir	28.80	-0.75	0.2260	0.43
		Control	36.81
	No	Remdesivir	46.23	2.38	0.0087	1.76
		Control	13.22
Low	Yes	Remdesivir	13.99	-0.33	0.3712	0.09
		Control	15.72
	No	Remdesivir	8.79	-2.06	0.0199	1.38
		Control	34.72
Outcome: Probability of being on a ventilator
D dimers	Diabetes	Condition	% on ventilator	Z	p	Risk ratio
High	Yes	Remdesivir	6.16	-1.21	0.1125	0.11
		Control	55.34
	No	Remdesivir	67.92	-0.07	0.4708	0.90
		Control	75.47
Low	Yes	Remdesivir	8.22	0.27	0.3955	1.62
		Control	5.07
	No	Remdesivir	0.00	-4.45	< 0.0001	0.00
		Control	75.66
Outcome: Time to mortality
D dimers	Diabetes	Condition	Hazard ratio	Z	p	Risk ratio
High	Yes	Remdesivir	-3.13	0.11	0.4570	5.78
		Control	-4.92
	No	Remdesivir	-5.98	-0.02	0.4930	0.89
		Control	-5.86
Low	Yes	Remdesivir	-4.84	-0.12	0.4512	0.52
		Control	-4.17
	No	Remdesivir	-5.03	-2.72	0.0032	0.01
		Control	0.00

Cohen’s d effect size is conventionally defined as small = 0.2, medium = 0.5, and large = 0.8. Effect sizes for risk ratios are conventionally defined as small = 0.60 or 1.68, medium = 0.29 or 3.47, and large = 0.15 or 6.71.