Sequential organ failure assessment score is superior to other prognostic indices in acute pancreatitis

doi:10.5492/wjccm.v10.i6.355

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Nov 9, 2021 (publication date) through Nov 5, 2024

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World Journal of Critical Care Medicine

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2220-3141

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Crit Care Med. Nov 9, 2021; 10(6): 355-368
Published online Nov 9, 2021. doi: 10.5492/wjccm.v10.i6.355

Table 1 Demographic and clinical profile of patients with acute pancreatitis n (%)

Characteristic	Overall study population (n = 653)	Mild to moderately severe AP (n = 572)	Severe AP (n = 81)	P value
Mean age at admission (Range)	58.7 ± 17.5 (20-98)	57.9 ± 17.0 (20-95)	64.2 ± 20.0 (20-98)	0.002^a
Gender
Male	383 (58.7)	334 (58.4)	49 (60.5)	0.285
Ethnicity				0.099
Chinese	458 (70.1)	391 (68.4)	67 (82.7)
Malay	43 (6.6)	36 (6.3)	7 (8.6)
Indian	108 (16.5)	102 (17.8)	6 (7.4)
Others	44 (6.7)	43 (7.5)	1 (1.2)
Comorbidities
Hypertension	339 (51.9)	283 (49.5)	56 (69.1)	0.005^a
T2DM	204 (31.2)	168 (29.4)	36 (44.4)	0.025^a
Hyperlipidemia	235 (36)	198 (34.6)	37 (45.7)	0.373
Ischaemic heart disease	81 (12.4)	63 (11.0)	18 (22.2)	0.012^a
Cerebrovascular disease	51 (7.8)	43 (7.5)	8 (9.9)	0.768
Renal impairment	42 (6.4)	33 (5.8)	9 (11.1)	0.195
COPD	13 (2.0)	9 (1.6)	4 (4.9)	0.217
Asthma	37 (5.7)	33 (5.8)	4 (4.9)	0.038^a
Others	120 (18.4)	107 (18.7)	13 (16.0)	0.919
Medications
Immunosuppressed	2 (0.3)	2 (0.3)	0	0.467
Steroids	9 (1.4)	6 (1.0)	3 (3.7)	0.214
Anticoagulants	32 (4.9)	24 (4.2)	8 (9.9)	0.065
History of smoking	125 (19.1)	118 (20.5)	7 (8.6)	0.042^a
History of alcohol consumption	159 (24.4)	145 (25.4)	14 (17.3)	0.454
Previous pancreatic disease	76 (11.6)	67 (11.7)	9 (11.1)	0.112
Chronic pancreatitis	30 (4.6)	29 (5.1)	1 (1.2)	0.098
Previous Cholecystectomy	44 (6.7)	38 (6.6)	6 (7.4)	0.809
Etiology
Gallstones	404 (61.9)	350 (61.2)	54 (66.7)	0.390
Alcohol	38 (5.8)	34 (5.9)	4 (4.9)	0.437
Idiopathic	61 (9.3)	52 (9.1)	9 (11.1)	0.634
Hypertriglyceridemia	19 (2.9)	14 (2.4)	5 (6.2)	0.161
Autoimmune	4 (0.6)	4 (0.7)	0	0.491
Hypercalcemia	3 (0.5)	2 (0.3)	1 (1.2)	0.235
Drug induced	6 (0.9)	3 (0.5)	3 (3.7)	0.065
Others	47(7.2)	44 (7.7)	3 (3.7)	0.343

^aP < 0.05. T2DM: Type 2 diabetes mellitus; COPD: Chronic obstructive pulmonary disease; AP: Acute pancreatitis; Idiopathic: Acute pancreatitis with no etiology despite extensive work up; Others: Etiologies of acute pancreatitis include trauma, pancreas cystic neoplasms, malignancy, iatrogenic causes such as endoscopic retrograde cholangiopancreatography.

Citation: Teng TZJ, Tan JKT, Baey S, Gunasekaran SK, Junnarkar SP, Low JK, Huey CWT, Shelat VG. Sequential organ failure assessment score is superior to other prognostic indices in acute pancreatitis . World J Crit Care Med 2021; 10(6): 355-368
URL: https://www.wjgnet.com/2220-3141/full/v10/i6/355.htm
DOI: https://dx.doi.org/10.5492/wjccm.v10.i6.355