Copyright
©2012 Baishideng.
World J Crit Care Med. Jun 4, 2012; 1(3): 80-93
Published online Jun 4, 2012. doi: 10.5492/wjccm.v1.i3.80
Published online Jun 4, 2012. doi: 10.5492/wjccm.v1.i3.80
Table 1 The effects of general anesthetics on ion channels
| Volatile anesthetics | Intravenous anesthetics | |||||||||
| Halothane | Isoflurane | Enflurane | Ether | Ethanol | Propofol | Etomidate | Ketamine | Phentobarbital | Benzodiazepine | |
| GABAA | + | + | + | + | + | + | + | -- | + | + |
| hα1β1 | + | + | + | |||||||
| hα1β2 | + | + | + | + | + | + | + | |||
| hα1β1γ2 | + | + | + | + | + | + | ||||
| hα1β2γ2 | + | + | + | |||||||
| NMDA | -- | -- | -- | -- | -- | -- | ||||
| AMPA/Kainate | ||||||||||
| GluR1 | -- | -- | ||||||||
| GluR3 | -- | -- | -- | -- | ||||||
| GluR2 + 3 | -- | -- | -- | -- | ||||||
| GluR6 | + | + | + | -- | + | -- | ||||
| K+ | ||||||||||
| KV | -- | -- | -- | -- | -- | |||||
| TREK | +/-- | +/-- | +/-- | +/-- | +/-- | |||||
| HCN | -- | -- | -- | -- | ||||||
| Na+ | -- | -- | -- | -- | -- | -- | ||||
- Citation: Zhou C, Liu J, Chen XD. General anesthesia mediated by effects on ion channels. World J Crit Care Med 2012; 1(3): 80-93
- URL: https://www.wjgnet.com/2220-3141/full/v1/i3/80.htm
- DOI: https://dx.doi.org/10.5492/wjccm.v1.i3.80